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Linda Crnic Institute for Down Syndrome

Linda Crnic Institute for Down Syndrome

12700 East 19th Avenue, Aurora (CO), 80045, United States

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(303) 724-6599

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About Improving the lives of people with Down syndrome. Home of the Human Trisome Project. Part of the University of Colorado Anschutz Medical Campus.
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Description Down syndrome is caused when an individual is born with a third copy of chromosome 21, an event called trisomy 21. Trisomy 21 occurs in 1 every ~700 live births, making it the most common chromosomal abnormality in the human population. Trisomy 21 impacts the development of nearly every major organ system in the body, which causes individuals with Down syndrome to experience a different array of health problems than the typical population. Interestingly, people with Down syndrome are protected from developing some medical conditions, such as most solid tumors, while being strongly predisposed to developing others, such as Alzheimer’s disease and autoimmune disorders.

The Crnic Institute’s Human Trisome Project™ arises from the fundamental belief that all human beings are equally worthy of medical care and research, regardless of their genetic make-up, and that all individuals can make significant contributions to our society. The Human Trisome Project will transform the population with trisomy 21 into one of the best studied groups of human beings in the world. The main goal of the Crnic HTP is to elucidate how trisomy 21 causes a different disease spectrum, protecting from some conditions while predisposing to others. This project will serve individuals with Down syndrome first and foremost, but also greatly benefit all humankind.
Founded 2008
  • 12700 East 19th Avenue, Aurora (CO), 80045, United States
  • Get Directions